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New Breakthrough Treatment Could Cure Thousands of High Blood Pressure Cases

Monday, March 10, 2025 / No Comments

 

Primary aldosteronism can send someone’s blood pressure as high as 200/130, far above the 120/80 level doctors say is healthy. Photograph: SDI Productions/Getty ImagesA groundbreaking treatment could offer a cure for half a million people in the UK suffering from dangerously high blood pressure, a condition often referred to as a “silent killer” due to its lack of symptoms and high risk of heart attacks and strokes.

Researchers in London and Cambridge have developed a minimally invasive procedure called targeted thermal therapy (TTT) to tackle primary aldosteronism, a condition responsible for 5% of all high blood pressure cases. This condition occurs when small nodules on the adrenal glands cause excessive salt retention in the body, leading to dangerously high blood pressure levels—sometimes reaching 200/130, far above the healthy 120/80 range.

A Quick and Effective Alternative

TTT, also known as endoscopic ultrasound-guided radiofrequency ablation, works by using short bursts of heat to destroy the nodules causing excessive aldosterone production. Unlike traditional surgery to remove an entire adrenal gland, which requires general anesthesia and a hospital stay of several days, TTT takes just 20 minutes under sedation, allowing patients to go home the same day.

A recent 28-patient trial, published in The Lancet, showed promising results:

  • 4 patients were able to stop taking medication entirely.
  • 12 patients saw significant improvements in blood pressure or needed fewer drugs.
  • The treatment successfully reduced excess aldosterone production in 75% of participants.

Transforming Lives

Professor Morris Brown, an expert in endocrine hypertension at Queen Mary University of London and Barts Health NHS Trust, believes this technique could be life-changing for many. “For years, people with this type of high blood pressure had no real alternative to daily medication or major surgery,” he said. “Now, we can remove the problem at its source with a simple procedure and some patients see their blood pressure return to normal the very next day.”

The treatment is currently being tested in a larger 110-patient trial to further assess its effectiveness.

Dr. Pauline Swift, chair of Blood Pressure UK, called the findings “very encouraging” and highlighted the potential for thousands of people to benefit from the new therapy. “High blood pressure is a leading cause of heart attacks, strokes, and kidney disease, yet it often goes unnoticed until serious complications arise,” she said.

If larger trials confirm these promising results, TTT could become a game-changer for those struggling with hypertension due to primary aldosteronism, offering them a safe, effective, and long-term solution.

Archaeologists Discover Oldest Known Bone Tools in Tanzania

Wednesday, March 5, 2025 / No Comments

 

The 27 bone tools that archaeologists uncovered in Tanzania varied in size depending on which animal from which they originated. - CSICIn a groundbreaking discovery, archaeologists have uncovered 1.5 million-year-old bone tools in northern Tanzania, making them the oldest known of their kind by nearly a million years. The findings challenge previous assumptions about early human technology and cognition.

Historic Discovery in Olduvai Gorge

The tools, found in the Olduvai Gorge, were made from elephant and hippopotamus bones and show clear signs of being sharpened and shaped, likely with stone tools. The 27 bone fragments, some nearly 15 inches long, suggest that early human ancestors systematically produced these tools using techniques similar to stone toolmaking.

Previously, the earliest known bone tools dated back 250,000 to 500,000 years in Europe. This discovery, published in Nature, pushes that timeline back significantly, offering new insights into early hominin intelligence.

Cognitive Breakthrough for Early Humans

Researchers believe the tools demonstrate that early humans were capable of abstract reasoning, recognizing patterns, and applying learned techniques across different materials."This expansion of technological potential indicates advances in cognitive abilities" said Dr. Ignacio de la Torre, lead author of the study.

New Questions About Early Human Behavior

The discovery raises several questions:

  • Who made these tools? While no human remains were found at the site, Homo erectus and Paranthropus boisei are believed to have lived in the region at the time.
  • How were they used? While direct evidence is lacking, researchers suspect the tools were used for processing animal carcasses and crafting additional tools.
  • Why were they made from bone? Some experts suggest bone was an alternative to stone, especially in areas where rocks were scarce.

Dr. Briana Pobiner, a paleoanthropologist at the Smithsonian, called the find “a signal that toolmaking was becoming an increasingly important part of our ancestors’ lives.”

This discovery reshapes our understanding of early technology and suggests that early human ancestors were far more advanced than previously thought.

Study Finds Bacterial Vaginosis Can Be Transmitted by Male Partners

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In one group, women and their male partners were given tablets and topical cream, and in the other, only the women received the treatment. Photograph: alvarez/Getty ImagesA new study has found that bacterial vaginosis (BV) can be passed to women by their male sexual partners, challenging long-standing beliefs that the condition is not a sexually transmitted infection (STI).

Published in the New England Journal of Medicine, the study suggests that treating male partners significantly reduces the risk of BV recurrence, potentially reshaping how the infection is managed.

Breakthrough Research

Australian researchers studied monogamous, heterosexual couples where the women had BV. One group received treatment for both the woman and her male partner, while another group treated only the woman.

The results were striking:

  • BV returned in 35% of women whose partners were also treated.
  • 63% of women in the other group—who were treated alone—saw their infection return.
  • Women with treated partners also went longer without experiencing a recurrence.

The findings were so significant that the trial was halted early due to the clear benefits of treating both partners.

Challenge to Medical Guidelines

BV is one of the most common vaginal infections, affecting up to a third of reproductive-aged women. While it is known to be triggered by sexual activity, it has not traditionally been classified as an STI.

Experts say the study provides strong evidence that BV can be sexually transmitted and could lead to new treatment approaches.

Dr. Janet Wilson, a consultant in sexual health, called the research a “big step forward” and criticized the UK’s NHS website for providing “outdated and misleading” information on BV. She urged for medical guidelines to be updated in light of the findings.

With this discovery, BV treatment could soon change worldwide, offering better outcomes for millions of women.

Scientists Develop ‘e-Taste’ Device to Simulate Flavors in Virtual Reality

Sunday, March 2, 2025 / No Comments

 

Sharing smells or tastes remotely has proved to be a challenge for scientists. Photograph: JohnnyGreig/Getty ImagesScientists have developed a groundbreaking device capable of recreating flavors digitally, a development that could transform virtual reality experiences, online shopping, and even weight management.

The device, known as e-Taste, allows users to experience the taste of food and drinks remotely. According to a study published in Science Advances, the system consists of two key components: an electronic tongue, which analyzes the chemical composition of a food or beverage, and a delivery system that recreates the taste using a mix of edible chemicals.

The device replicates five basic taste sensations—sweet, sour, salty, bitter, and umami—by precisely releasing corresponding chemicals onto the tongue. However, researchers note that certain sensations, such as spiciness and fattiness, are not yet reproducible.

In trials, participants successfully identified flavors with high accuracy, suggesting the technology could have widespread applications beyond entertainment, including biomedical research and sensory testing.

Experts believe the device marks a significant step toward integrating taste into digital experiences, though further development is needed before it can be widely adopted.

Fossil Discovery in China Reshapes the Timeline of Bird Evolution

Saturday, March 1, 2025 / No Comments

 

An artist’s impression of the Baminornis zhenghensis bird, released on Wednesday.Chuang Zhao via ReutersA newly discovered fossil from southeastern China is rewriting the history of avian evolution, revealing that birds with modern anatomical features soared through the skies millions of years earlier than previously believed.

The fossil, named Baminornis zhenghensis, was found in Zhenghe County, Fujian province, and dates back approximately 150 million years to the Jurassic period. Published in the journal Nature, this discovery places Baminornis among the oldest known birds, alongside Archaeopteryx, the famed “first bird” fossil unearthed in Germany in 1862.

“For over 150 years, Archaeopteryx has stood alone as the only undisputed bird fossil from the Jurassic period,” said Steve Brusatte, a paleontologist at the University of Edinburgh. “This new fossil changes that.”

A Missing Link in Evolution

Though other birdlike fossils from the Jurassic have been found, scientists have long puzzled over the lack of confirmed bird specimens from that era. If Archaeopteryx was already flying, logic suggested that other birds must have existed too. The discovery of Baminornis fills this long-standing gap in the fossil record, making it the second confirmed bird from the Jurassic period.

Lead researcher Min Wang, from the Institute of Vertebrate Paleontology and Paleoanthropology at the Chinese Academy of Sciences, called the find “very exciting.”

“These fossils fundamentally change our understanding of early bird evolution,” Wang told NBC News. “They show that birds originated much earlier than we previously thought.”

What Makes Baminornis Different?

Unlike Archaeopteryx, which had a long, reptile-like tail, Baminornis featured a pygostyle—a fused set of tail vertebrae similar to those found in modern birds. This shorter tail, a crucial aerodynamic feature, shifted the bird’s center of mass toward its wings, allowing for improved flight.

Until now, such adaptations were believed to have evolved at least 20 million years later, seen in birds like Eoconfuciusornis and Protopteryx.

“What excites me most is that Baminornis was a more advanced flyer than Archaeopteryx,” Brusatte said. “It shows that bird evolution was already in full swing during the Jurassic.”

The fossilized remains of Baminornis—found alongside numerous aquatic and semiaquatic species in what researchers are calling the “Zhenghe Fauna” collection—suggest a diverse ecosystem. So far, at least three fossils from this site appear to belong to early birds or their closest relatives, hinting at a broader range of Jurassic avian species yet to be uncovered.

Unanswered Questions

Although the fossil preserves much of Baminornis’ skeleton, its feathers were not fossilized, leaving gaps in understanding its wing structure and flight mechanics. The absence of a skull also limits knowledge about its diet.

Still, the discovery suggests that bird evolution began as early as 164 to 172 million years ago—pushing back previous estimates by millions of years.

Baminornis tells us that birds were already diversifying in the Jurassic, developing different flight styles and adaptations,” Brusatte said.

With more fossils from the Zhenghe Fauna yet to be studied, researchers are optimistic that future discoveries will continue to reshape our understanding of how modern birds evolved from their dinosaur ancestors.

Rare Seven-Planet Alignment to Light Up the Night Sky

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Mercury, Venus, Mars, Jupiter, Saturn, Uranus and Neptune lined up horizontally in a ‘planetary parade’. Illustration: Alamy/PAOn the final day of February, skywatchers will witness a spectacular celestial event-a "planetary parade" where seven planets align in a rare cosmic display.

This phenomenon occurs when multiple planets appear to form a straight line in the night sky. According to Dr. Greg Brown, an astronomer at the Royal Observatory Greenwich, “A planetary parade happens when several planets become visible at the same time. The spectacle’s impact depends on the number of planets involved and how easily they can be seen.”

While all seven planets—Mercury, Venus, Mars, Jupiter, Saturn, Uranus, and Neptune—will technically align, some will be more visible than others. Brown explains that Mercury, Neptune, and Saturn will be positioned near the horizon, making them challenging to spot, particularly in the fading twilight. Uranus and Neptune, both faint and distant, will require a telescope or binoculars. However, Venus, Jupiter, and Mars will be bright and easily visible to the naked eye.

How and When to Watch

Planetary alignments occur because all the planets orbit the Sun within the same general plane, known as the ecliptic. As they move at different speeds and distances, there are moments when they appear to align from Earth’s perspective.

Dr. Shyam Balaji, a researcher in astroparticle physics and cosmology at King’s College London, advises that the best viewing time for the UK is shortly after sunset on 28 February, when the planets will be visible above the western horizon. Similar viewing conditions apply in the US (about 30 minutes after sunset) and Australia (looking north after sunset). For the best experience, stargazers should avoid bright city lights and consider using stargazing apps to locate the planets.

While planetary groupings of three to five planets are relatively common, full seven-planet alignments are rare, with the next one not expected until 2040. A similar event occurred last June, but only two planets were visible without special equipment. This month, Venus, Mars, and Jupiter will be the easiest to spot, while Saturn and Mercury will be near the horizon, making them more difficult to observe. Uranus and Neptune, though included in the alignment, will require binoculars or a telescope.

For those using telescopes, Brown suggests looking for the moons of Jupiter or the crescent shape of Venus to enhance the experience. As spring progresses, the planets will slowly drift apart, making this a fleeting but awe-inspiring moment in the night sky.

Mark Your Calendar

This planetary parade is a rare opportunity for both amateur and seasoned astronomers to witness the planets in alignment. Whether gazing with the naked eye or through a telescope, this celestial event offers a breathtaking reminder of the vastness of our solar system.

Ancient Glaciers Shaped Earth's Evolution, New Study Suggests

Thursday, February 27, 2025 / No Comments

 

Ancient glaciers reshaped Earth’s surface and shifted ocean chemistry, fueling the rise of complex life, a new study found. Calved icebergs from the Twin Glaciers are seen in 2013 off Greenland's coast. - Joe Raedle/Getty Images/FILEA groundbreaking study has revealed how ancient glaciers not only reshaped Earth's surface but also altered ocean chemistry, potentially setting the stage for the rise of complex life forms.

During the Neoproterozoic Era, also known as “Snowball Earth”, which spanned from approximately 1 billion to 543 million years ago, glaciers carved through landmasses, scraping minerals from Earth's crust. As these glaciers melted, they released a surge of nutrients into the oceans, which may have been crucial in fostering the evolution of complex organisms.

Glacial 'Broom' Swept the Oceans Clean

The glaciers acted as a massive "glacial broom," scouring the ground beneath them and depositing mineral-rich sediments into the seas. These nutrients likely played a role in the development of more sophisticated marine life, evolving from early simple forms such as microbes and sponges to creatures with shells, armor, and spikes.

Scientists have long believed that increased oxygen levels contributed to this evolutionary leap. However, the new research, published in the journal Geology, suggests that the glacier-driven changes to ocean chemistry may have been equally significant.

A Glimpse into Earth's Deep Past

The research team, led by Dr. Chris Kirkland from Curtin University in Australia, examined ancient sediments in Scotland and Northern Ireland. By analyzing zircons—durable crystals that act as geological timekeepers—the scientists traced changes in Earth's crust and ocean chemistry during this icy era.

The study found that sediment compositions during Snowball Earth differed significantly from those in the subsequent “hothouse Earth” period, when ice retreated, and the planet warmed. These shifts indicated active glaciation, suggesting that glaciers were not static but moved, eroded the ground, and influenced ocean chemistry.

Evolving the Blueprint for Life

The research also uncovered a link between glacial erosion and increased nutrients in the oceans. The gradual thawing of Earth’s ice cover led to significant chemical changes, including a rise in oceanic and atmospheric oxygen. This shift could have provided the necessary boost for primitive life to evolve into more complex organisms.

While some scientists remain cautious about drawing direct lines between glacial activity and biological evolution, the study adds weight to the theory that Earth’s icy past helped shape the biodiversity we see today.

Modern Parallels: Climate Change Lessons

The study also offers valuable insights into modern climate change. Unlike the slow-moving changes of the Neoproterozoic, today's climate crisis is accelerating rapidly. The research underscores how altering one component of Earth's system—such as increasing carbon dioxide levels—can trigger widespread and potentially irreversible changes.

“Our geological record shows that changing one part of Earth affects another,” said Dr. Kirkland. “With the current pace of human-driven climate change, the planet’s natural ability to regulate itself is being put to the test.”

A Continuing Scientific Conversation

While the findings introduce new perspectives on the relationship between glaciation and evolution, experts agree that further research is needed. Dr. Andrew Knoll of Harvard University noted that while the study presents an interesting hypothesis, the full impact of glacially-delivered nutrients on long-term biological development remains an open question.

As scientists continue to decode Earth’s ancient past, each discovery adds a piece to the puzzle—not only helping us understand our planet’s history but also guiding how we might navigate its future.