Scientists recreate mouse from gene older than animal life
The key innovation lies in the Sox gene, known for driving pluripotency—the ability of cells to develop into any type of tissue. Researchers extracted this gene from choanoflagellates and introduced it into mouse stem cells. These modified cells were then used to produce a living mouse, showcasing how genes pivotal to stem cell function existed even before multicellular life evolved.
Choanoflagellates are the closest known relatives of animals, making them crucial for understanding the evolutionary leap from single-celled organisms to complex life forms. The study underscores the deep evolutionary connections shared by all life on Earth and highlights the potential of ancient genetic tools in modern science.
This research not only expands our understanding of stem cell origins but also opens new doors for advancements in biotechnology and regenerative medicine.
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